Journal: Pharmaceutics

Article Title: Alectinib-Loaded Chitosan–Alginate Nanoparticles: A Novel Synthesis Method with In Vitro and In Vivo Evaluations

doi: 10.3390/pharmaceutics17040492

Figure Lengend Snippet: Figure 1. The inhibitory role of Alectinib on EML4-ALK-positive NSCLC.

Article Snippet: Alectinib hydrochloride was obtained from (Biosynth Zurich, Switzerland, distributed by Cymit Química S.L., Barcelona, Spain) while dimethyl sulfoxide (DMSO) was sourced from EMSURE® in Grove Village, IL, USA.

Techniques:

Journal: Pharmaceutics

Article Title: Alectinib-Loaded Chitosan–Alginate Nanoparticles: A Novel Synthesis Method with In Vitro and In Vivo Evaluations

doi: 10.3390/pharmaceutics17040492

Figure Lengend Snippet: Figure 3. The synthesis process of Alectinib-loaded chitosan–alginate nanoparticles.

Article Snippet: Alectinib hydrochloride was obtained from (Biosynth Zurich, Switzerland, distributed by Cymit Química S.L., Barcelona, Spain) while dimethyl sulfoxide (DMSO) was sourced from EMSURE® in Grove Village, IL, USA.

Techniques:

Journal: Pharmaceutics

Article Title: Alectinib-Loaded Chitosan–Alginate Nanoparticles: A Novel Synthesis Method with In Vitro and In Vivo Evaluations

doi: 10.3390/pharmaceutics17040492

Figure Lengend Snippet: Figure 5. The chromatogram of Alectinib 12.5 µg/mL solution in methanol and the chromatogram of the mobile phase.

Article Snippet: Alectinib hydrochloride was obtained from (Biosynth Zurich, Switzerland, distributed by Cymit Química S.L., Barcelona, Spain) while dimethyl sulfoxide (DMSO) was sourced from EMSURE® in Grove Village, IL, USA.

Techniques:

Journal: Pharmaceutics

Article Title: Alectinib-Loaded Chitosan–Alginate Nanoparticles: A Novel Synthesis Method with In Vitro and In Vivo Evaluations

doi: 10.3390/pharmaceutics17040492

Figure Lengend Snippet: Figure 7. The FTIR spectra of Alectinib, chitosan, alginate, and their mixture.

Article Snippet: Alectinib hydrochloride was obtained from (Biosynth Zurich, Switzerland, distributed by Cymit Química S.L., Barcelona, Spain) while dimethyl sulfoxide (DMSO) was sourced from EMSURE® in Grove Village, IL, USA.

Techniques:

Journal: Pharmaceutics

Article Title: Alectinib-Loaded Chitosan–Alginate Nanoparticles: A Novel Synthesis Method with In Vitro and In Vivo Evaluations

doi: 10.3390/pharmaceutics17040492

Figure Lengend Snippet: Figure 8. DSC thermograms of pure Alectinib, chitosan, alginate, and ACANPs showing changes in thermal behavior, indicating drug encapsulation and transformation into the amorphous state.

Article Snippet: Alectinib hydrochloride was obtained from (Biosynth Zurich, Switzerland, distributed by Cymit Química S.L., Barcelona, Spain) while dimethyl sulfoxide (DMSO) was sourced from EMSURE® in Grove Village, IL, USA.

Techniques: Encapsulation, Transformation Assay

Journal: Pharmaceutics

Article Title: Alectinib-Loaded Chitosan–Alginate Nanoparticles: A Novel Synthesis Method with In Vitro and In Vivo Evaluations

doi: 10.3390/pharmaceutics17040492

Figure Lengend Snippet: Figure 11. (A) LC-MS/MS chromatogram for the blank sample with no peak of Alectinib. (B) Alectinib at 483,300 Da, height: 2.48 × 103 cps, RT: 0.504 min. (C) Rosuvastatin (internal standard) at 482,200 Da, height: 1.64 × 105 cps, RT: 0.750 min.

Article Snippet: Alectinib hydrochloride was obtained from (Biosynth Zurich, Switzerland, distributed by Cymit Química S.L., Barcelona, Spain) while dimethyl sulfoxide (DMSO) was sourced from EMSURE® in Grove Village, IL, USA.

Techniques: Liquid Chromatography with Mass Spectroscopy

Journal: iScience

Article Title: AXL and SHC1 confer crizotinib resistance in patient-derived xenograft model of ALK-driven lung cancer

doi: 10.1016/j.isci.2024.110846

Figure Lengend Snippet:

Article Snippet: Alectinb , Selleck Chemicals , Cat#S5232.

Techniques: Recombinant, Proliferation Assay, cDNA Synthesis, Multiplex Assay, Sequencing, Mass Spectrometry, DNA Sequencing